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डायलिसिस की एक विधि जो प्रसार (डिफ्यूजन) और संवहन (कन्वेक्शन) दोनों जोड़ती है — बड़े विषाक्त पदार्थों को हटाने में मानक HD से अधिक प्रभावी। ऑनलाइन HDF के लिए अल्ट्रा-शुद्ध डायलिसेट की आवश्यकता होती है।
Hemodiafiltration (HDF) combines diffusive clearance (as in standard HD) with convective clearance via ultrafiltration and simultaneous substitution fluid replacement. Online HDF (ol-HDF) uses freshly generated ultrapure dialysate as substitution fluid. The ESHOL study (Maduell et al., 2013, JASN) demonstrated a 30% reduction in all-cause mortality with high-volume HDF (convective volume >23 L/session) compared to standard HD. Other trials (CONTRAST, Turkish HDF Study) showed trends toward improved survival in subgroups. Key parameters include substitution volume target (≥23 L/session for post-dilution HDF), ultrapure dialysate (endotoxin <0.03 EU/mL), and convective clearance monitoring.
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This content is a general reference, not medical advice, a diagnosis, or a treatment plan. Do not change your diet, fluids, medicines, or dialysis plan without your nephrologist or renal dietitian. Individual recommendations depend on your labs, medications, conditions, and care plan.