किडनी ट्रांसप्लांट क्या है?

विस्तृत जानकारी

Kidney transplantation provides the best long-term outcomes for ESRD patients with superior survival, quality of life, and lower costs compared to long-term dialysis. One-year graft survival rates: living donor — 95-98%, deceased donor — 90-95%. Half-life for deceased donor grafts is approximately 10-12 years. Pre-transplant evaluation includes: cardiac and pulmonary assessment, malignancy screening, infection workup, tissue typing (HLA matching), and crossmatch testing. Immunosuppression typically includes induction (anti-thymocyte globulin or basiliximab) and maintenance (tacrolimus + mycophenolate mofetil + prednisone). Post-transplant complications: acute rejection (10-20% in first year), infections (CMV, BK virus), cardiovascular disease (leading cause of death post-transplant), and post-transplant diabetes. Pre-emptive transplant (before dialysis initiation) offers the best outcomes.

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