What causes eGFR 40 mL/min/1.73mÂ²?

Advanced chronic kidney disease

What should I do if my eGFR is 40?

Nephrology follow-up every 3-6 months Monitor anemia, bone-mineral markers, potassium Keep proteinuria treated (ACEi/ARB, SGLT2i)

Advanced chronic kidney disease

What should I do about eGFR 40?

Nephrology follow-up every 3-6 months Monitor anemia, bone-mineral markers, potassium Keep proteinuria treated (ACEi/ARB, SGLT2i)

eGFR — Stage G3b

eGFR 40 mL/min/1.73mÂ²: What It Means

Classification: Stage G3b

eGFR 40 is stage G3b — moderate-severe reduction. Progression risk is meaningful, and specialist monitoring is standard of care.

What can cause this?

Advanced chronic kidney disease

Your next steps

1Nephrology follow-up every 3-6 months
2Monitor anemia, bone-mineral markers, potassium
3Keep proteinuria treated (ACEi/ARB, SGLT2i)

About the eGFR test

Estimated glomerular filtration rate — the best overall measure of kidney function. It is calculated from creatinine, age, and sex (CKD-EPI 2021 equation) and used to stage chronic kidney disease.

Calculated from a serum creatinine blood test. No extra sample needed — labs report eGFR automatically with any creatinine.

Reference: KDIGO CKD classification; CKD-EPI 2021 equation (NEJM 2021) • Normal range: â‰¥90 mL/min/1.73mÂ² (declines with age)

Use the eGFR tool

Calculate and interpret your value properly

Other eGFR Values

90 mL/min/1.73mÂ² 75 mL/min/1.73mÂ² 60 mL/min/1.73mÂ² 55 mL/min/1.73mÂ² 50 mL/min/1.73mÂ² 45 mL/min/1.73mÂ² 35 mL/min/1.73mÂ² 30 mL/min/1.73mÂ² 25 mL/min/1.73mÂ² 20 mL/min/1.73mÂ² 15 mL/min/1.73mÂ² 18 mL/min/1.73mÂ²

This page is educational and not a diagnosis — interpret with your healthcare provider.

eGFR 40: Quick Answers

Kidney Function & eGFR

eGFR calculator (CKD-EPI 2021)eGFR decline & time-to-failure estimator Creatinine 1.3 — is it normal?eGFR 45 — what it means What is eGFR?Can kidney disease be reversed?

Keep learning about eGFR

Tool: eGFR Calculator (CKD-EPI 2021)Lab: eGFR 90 Lab: eGFR 75 Lab: eGFR 60 Topic: Kidney Diet Basics: Potassium, Phosphorus & Sodium Explained Topic: Protein in Urine: Causes and What It Means

eGFR — Stage G3b

eGFR 40 mL/min/1.73mÂ²: What It Means

Classification: Stage G3b

eGFR 40 is stage G3b — moderate-severe reduction. Progression risk is meaningful, and specialist monitoring is standard of care.

What can cause this?

Advanced chronic kidney disease

Your next steps

1Nephrology follow-up every 3-6 months
2Monitor anemia, bone-mineral markers, potassium
3Keep proteinuria treated (ACEi/ARB, SGLT2i)

About the eGFR test

Estimated glomerular filtration rate — the best overall measure of kidney function. It is calculated from creatinine, age, and sex (CKD-EPI 2021 equation) and used to stage chronic kidney disease.

Calculated from a serum creatinine blood test. No extra sample needed — labs report eGFR automatically with any creatinine.

Reference: KDIGO CKD classification; CKD-EPI 2021 equation (NEJM 2021) • Normal range: â‰¥90 mL/min/1.73mÂ² (declines with age)

Use the eGFR tool

Calculate and interpret your value properly

Other eGFR Values

This page is educational and not a diagnosis — interpret with your healthcare provider.

eGFR 40: Quick Answers

Kidney Function & eGFR

eGFR calculator (CKD-EPI 2021)eGFR decline & time-to-failure estimator Creatinine 1.3 — is it normal?eGFR 45 — what it means What is eGFR?Can kidney disease be reversed?

Keep learning about eGFR

Tool: eGFR Calculator (CKD-EPI 2021)Lab: eGFR 90 Lab: eGFR 75 Lab: eGFR 60 Topic: Kidney Diet Basics: Potassium, Phosphorus & Sodium Explained Topic: Protein in Urine: Causes and What It Means

eGFR 40 mL/min/1.73mÂ²: What It Means

What can cause this?

Your next steps

About the eGFR test

Other eGFR Values

eGFR 40: Quick Answers

Kidney Function & eGFR

Keep learning about eGFR

Educational information only

Sources and methodology

eGFR 40 mL/min/1.73mÂ²: What It Means

What can cause this?

Your next steps

About the eGFR test

Other eGFR Values

eGFR 40: Quick Answers

Kidney Function & eGFR

Keep learning about eGFR

Educational information only

Sources and methodology

eGFR 40 mL/min/1.73mÂ²: What It Means

What can cause this?

Your next steps

About the eGFR test

Other eGFR Values

eGFR 40: Quick Answers

Is eGFR 40 mL/min/1.73mÂ² normal?

What causes eGFR 40?

What should I do about eGFR 40?

Kidney Function & eGFR

Keep learning about eGFR

Educational information only

Sources and methodology

eGFR 40 mL/min/1.73mÂ²: What It Means

What can cause this?

Your next steps

About the eGFR test

Other eGFR Values

eGFR 40: Quick Answers

Is eGFR 40 mL/min/1.73mÂ² normal?

What causes eGFR 40?

What should I do about eGFR 40?

Kidney Function & eGFR

Keep learning about eGFR

Educational information only

Sources and methodology