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Antibodies against the glomerular basement membrane causing rapidly progressive nephritis with lung hemorrhage.
Anti-GBM disease attacks kidney and lung basement membranes: RPGN with hemoptysis. Treatment is urgent plasmapheresis plus cyclophosphamide and steroids. Outcomes depend on presenting creatinine — dialysis-dependent patients rarely recover kidney function, but lung disease responds.
Glomerulonephritis with rapid loss of kidney function over days to weeks — a nephrology emergency.
Rapidly progressive glomerulonephritis with crescent-shaped cellular scars in the kidney filters — a medical emergency that can destroy kidney function in weeks.
Blood in the urine — visible (gross) or microscopic — with causes ranging from infection and stones to glomerulonephritis and malignancy.
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This content is a general reference, not medical advice, a diagnosis, or a treatment plan. Do not change your diet, fluids, medicines, or dialysis plan without your nephrologist or renal dietitian. Individual recommendations depend on your labs, medications, conditions, and care plan.